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Acrobat - View as HTML An interaction between medications does not always mean that you must stop taking one of them. The following medications may affect the way pioglitazone. What are the possible side effects of pioglitazone? What other drugs will affect pioglitazone? Where can I get more information? What does my medication. ACTOS works by directly targeting insulin resistance, a condition in which the body does not effectively use the insulin Raleigh, North it produces to control blood. Side Effects Side Affect of Generic for Actos (Pioglitazone Hydrochloride). Beta-blockers,

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